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Year:
2010
| Volume: 18
| Issue: 1-2
| Pages: 32-35
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Case Report |
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ANTIESTROGEN THERAPY IN RECURENT OVARIAN CANCER RESULTING IN 28 MONTHS OF STABLE DISEASE: A CASE REPORT AND REVIEW OF THE LITERATURE
Rajul Kothari, Peter Argenta, Jeffrey Fowler, Jori Carter, William Shimp |
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DOI:
10.2298/AOO1002032K |
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Abstract: |
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Hormonal therapy for adjuvant treatment of ovarian cancer may provide a low toxicity option in some patients with refractory disease. A 53 year-old patient with stage IIIC papillary serous ovarian cancer previously treated with multiple chemotherapy regimens with platinum-resistant disease was treated with antiestrogen therapy for 28 months before requiring reinstitution of cytotoxic chemotherapy. Hormonal therapy may be effective in a subset of epithelial ovarian cancer patients with endocrine sensitivity and should be considered in the treatment of platinum-resistant patients. |
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Key words:
Ovarian Neoplasms; Antineoplastic Agents, Hormonal; Selective Estrogen Receptor Modulators; Tamoxifen; Aromatase |
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